"And in preparing for that I wanted to show the court that he was telling the truth. And what happened was, obviously he was a little herbalist at the time, there were no double blind clinical studies or anything like that. But he gave me literally thousands of letters that people wrote just saying, listen I had heart disease, I took your heart drops and I got well. Now I couldn't use those letters, as evidence in court because that's what's called hearsay. But I could call the authors of the letters. And so in preparing for the trial, on the trial day, I actually had five middle class professionals, who had all had heart disease, they had all had at least one open heart by-pass surgery, they all then continued to have heart disease because the mainstream system wasn't addressing why their arteries were clogging, and they all needed another open heart by-pass surgery to survive.
And here's where they differed, a couple of them were not willing to go through it again, they had had so many complications, and it would just buy them a short period of time anyways so they just said "No. Sorry I am not doing that, I would just rather die." And a couple of the others were just too weak that the doctors ethically couldn't put them through the surgery, they weren't likely to survive. All of them were not into natural health but now the mainstream system was a dead end for them. So they all turned to the natural health community, they all came across these heart drops, usually through a naturopathic doctors, and they all became well, they all went back to work, none of them had been able to work.
And that experience changed my thinking because when I was acting for Health Canada against this herbalist, I had what really is a mainstream view that if something isn't regulated by the government then it shouldn't be allowed on the market. I mean if I said, now I'm just going to dramatize here:
"Do you mean that some rogue herbalist could sell something that is unapproved of by Health Canada? Doesn't that sound dangerous?
That's the mind set I had. But in preparing for that trial I had to come to the exact opposite conclusion about those heart drops. The danger was removing them from the market. And at the time, this was about twelve years ago, I could have given you the names, addresses and phone numbers of literally thousands of Canadians whose lives depended on those heart drops. And it forced me to do a re-think, because for them, Health Canada's actions in trying to take them away actually presented an extremely significant danger, and it raised in my mind for the first time, wait a second, people have to be able to take responsibility for their own health. It's fine for the government to educate us, and watch out for the things that are truly dangerous but to say you can't have something because we haven't approved it, when your life depends on it, is a very different issue. And that's what woke me up to it, was actually that experience. And so ironically, it was Health Canada that created that experien
Wednesday, November 9, 2011
Saturday, November 5, 2011
Canadians Do Not Get Enough Fruits ansd Vegetables
Everyone today is aware of the
importance of a diet rich in plantbased
nutrients from vegetables and
fruit to prevent disease and ensure a
long, healthy life. Yet, many of us
do not achieve the 7 to 10 servings
of vegetables and fruits recommended
by the Canadian Food
Guide, 2008 Edition. Furthermore,
much of the fruits and vegetables
we do eat lack nutrients due to storage,
cooking, and poor soil conditions.
In addition, the use of pesticides
and chemicals reduce the
quality and safety of foods.
But there is a way to make up for
dietary shortfalls in quality and
nutrition: Consume specially formulated
green and fruit based
superfood concentrates like
GreenZone and Zambroza.
GreenZone is a convenient powdered
food supplement (available in
capsules, too) that can help you get
the plant-based nutrition you need
to enjoy optimum health.
In fact, GreenZone is so brimming
with nutrition it is considered
a whole “superfood.”
GreenZone provides balanced
nutrition following the 40-30-30
principle: 40 percent of calories
from carbohydrates, 30 percent
from proteins, and 30 percent from
fats. This balance allows
GreenZone to help maximize the
body's fat-burning and energyreleasing
mechanisms. It blends the
most nutritionally dense greens,
algaes and herbs for the best
Few Canadians get the
recommended amount of
fruits and vegetables
utilization by the body.
One of the first things you’ll
notice after taking GreenZone for
some time is stronger nails, healthier
hair and improved skin condition.
You’ll have increased vitality
and endurance. You’ll experience
less stress and fewer bouts with illness.
Because GreenZone is a low
glycemic food, many people also
report better control of their blood
sugar.
And for those looking to lose
weight, GreenZone increases your
metabolism without causing nervousness
or heart palpitations.
One serving of a whole food supplement
like GreenZone is nutritionally
equivalent to 6 servings of
healthy salad. Whole food supplements
also have one of the highest
ORAC scores (antioxidant potential)
of any fruit or vegetable.
Just as GreenZone satisfies your
body’s need for vegetable nutrition,
the fruit-juice blend, Zambroza,
meets your need for nutrients and
phytochemicals from fruit. Most
recently, Zambroza received one of
the highest antioxidant (ORAC) ratings
from an independent laboratory.
And no wonder! Zambroza contains
extracts and juices from some
of the most potent fruits in the
world like blueberry, mangosteen,
goji berry, raspberries, grapes,
grape seeds and even green tea.
Just a 1/2 ounce serving of
Zambroza is nutritionally
The Dirty Dozen
Called the Dirty Dozen, these
are the 12 most likely produce
items to be contaminated by
pesticides according to
research conducted by the
USDA and FDA:
• Apples
• Bell Peppers
• Celery
• Cherries
• Grapes (imported)
• Nectarines
• Peaches
• Pears
• Potatoes
• Red Raspberries
• Spinach
• Strawberries
equivalent to a serving of fruit.
Taken twice daily it’s powerful
defence against many of today’s
chronic health concerns. It’s also
delicious tasting.
Supplementing with “Superfood” concentrates can make up for
poor food choices and a lack of proper nutrition
importance of a diet rich in plantbased
nutrients from vegetables and
fruit to prevent disease and ensure a
long, healthy life. Yet, many of us
do not achieve the 7 to 10 servings
of vegetables and fruits recommended
by the Canadian Food
Guide, 2008 Edition. Furthermore,
much of the fruits and vegetables
we do eat lack nutrients due to storage,
cooking, and poor soil conditions.
In addition, the use of pesticides
and chemicals reduce the
quality and safety of foods.
But there is a way to make up for
dietary shortfalls in quality and
nutrition: Consume specially formulated
green and fruit based
superfood concentrates like
GreenZone and Zambroza.
GreenZone is a convenient powdered
food supplement (available in
capsules, too) that can help you get
the plant-based nutrition you need
to enjoy optimum health.
In fact, GreenZone is so brimming
with nutrition it is considered
a whole “superfood.”
GreenZone provides balanced
nutrition following the 40-30-30
principle: 40 percent of calories
from carbohydrates, 30 percent
from proteins, and 30 percent from
fats. This balance allows
GreenZone to help maximize the
body's fat-burning and energyreleasing
mechanisms. It blends the
most nutritionally dense greens,
algaes and herbs for the best
Few Canadians get the
recommended amount of
fruits and vegetables
utilization by the body.
One of the first things you’ll
notice after taking GreenZone for
some time is stronger nails, healthier
hair and improved skin condition.
You’ll have increased vitality
and endurance. You’ll experience
less stress and fewer bouts with illness.
Because GreenZone is a low
glycemic food, many people also
report better control of their blood
sugar.
And for those looking to lose
weight, GreenZone increases your
metabolism without causing nervousness
or heart palpitations.
One serving of a whole food supplement
like GreenZone is nutritionally
equivalent to 6 servings of
healthy salad. Whole food supplements
also have one of the highest
ORAC scores (antioxidant potential)
of any fruit or vegetable.
Just as GreenZone satisfies your
body’s need for vegetable nutrition,
the fruit-juice blend, Zambroza,
meets your need for nutrients and
phytochemicals from fruit. Most
recently, Zambroza received one of
the highest antioxidant (ORAC) ratings
from an independent laboratory.
And no wonder! Zambroza contains
extracts and juices from some
of the most potent fruits in the
world like blueberry, mangosteen,
goji berry, raspberries, grapes,
grape seeds and even green tea.
Just a 1/2 ounce serving of
Zambroza is nutritionally
The Dirty Dozen
Called the Dirty Dozen, these
are the 12 most likely produce
items to be contaminated by
pesticides according to
research conducted by the
USDA and FDA:
• Apples
• Bell Peppers
• Celery
• Cherries
• Grapes (imported)
• Nectarines
• Peaches
• Pears
• Potatoes
• Red Raspberries
• Spinach
• Strawberries
equivalent to a serving of fruit.
Taken twice daily it’s powerful
defence against many of today’s
chronic health concerns. It’s also
delicious tasting.
Supplementing with “Superfood” concentrates can make up for
poor food choices and a lack of proper nutrition
Dr Bill Keller on Zambroza
At Nature’s Sunshine, I firmly
believe that original basic science
research is of paramount
importance. I feel that this belief is
shared by my colleagues because
everyone recognizes the important
correlation between company prestige
and research that supports the
products that we sell. We ask fundamental
questions about product
benefits and then design experiments
that provide the answers.
This approach separates Nature’s
Sunshine from the competition.
After considerable thought, I have
listed below salient points that
define the importance of original
basic science research:
• Verifies and/or establishes
the identity of
actives from an ingredient
• Correlates benefits
with identified actives
• Substantiates the science
behind ingredient
claims
• Establishes ingredient
value
• Confirms Nature’s
Sunshine as an industry
leader through publication
in peer reviewed
scientific journals
• Honours the scientific
integrity of defining and characterizing
the highest quality products
available
• Instills a high degree of consumer
confidence
Again, recognizing, embracing,
and pursuing these points distinguishes
Nature’s Sunshine as a first
class nutritional supplement company.
I have known Professor Doug
Kinghorn for 30 years. He is a
world class scientist in the discipline
of natural product chemistry
(Pharmacognosy). Professor
Kinghorn occupies an endowed
research chair at the prestigious
Ohio State University.
Professor Kinghorn and I
have collaborated on many
projects that focus on
Nature’s Sunshine’s high
quality products. Zambroza
has been a major research
effort for the past four
years. Mangosteen
(Garcinia mangostana), the
core fruit of Zambroza, has
yielded some fascinating
research results.
Xanthones are a class of
plant chemicals that are
found abundantly in mangosteen.
Not only are
the xanthones powerful
Some Of The Science
Behind The Benefits Of
Zambroza™ And Paw Paw Common cold meets
its match in ancient herb
A University of Western Ontario
and University of Alberta team
found that ginseng extracts
"have been found to have the
potential to modulate both natural
and acquired immune
responses." The four-month test
involved 280 subjects between
18 and 65 years of age. At the
conclusion of the test 10% of
the ginseng group reported only
experiencing two or more colds
during the cold/flu season. More
than double that percentage
reported having caught colds in
the placebo group.
In another study from the
Journal of the American
Geriatric Society, 2004, 200 elderly
subjects were given either
ginseng extract or a placebo during
flu season. At the end of the
study, researchers found the
incidence of influenza was considerably
higher in the placebo
group than the ginseng group.
Hand washing best
prevention
According to Health Canada the
best prevention against catching
a virus is frequent hand washing.
Most germs are caught
through hand to eye, face and
mouth contact.
Healthy Bits
Nature’s News
News and information from the world of herbs and nutrition science
by William J. Keller, Ph.D.
Vol. 1/No. 1.
antioxidants, but we also believe
that they possess many other beneficial
effects. Our first scientific
investigation of mangosteen resulted
in the isolation of ten different
xanthones in chemically pure form
and three of these were new from
Nature. Once we determined the
chemical structure of these three
xanthones, we knew that no one
else had ever isolated them. These
pure xanthones were then shown to
have outstanding antioxidant activity.
Further evaluation of these isolated
xanthones suggested cancer
chemoprevention potential. These
data were first published as an
abstract and presented as a poster
paper at the Annual Meeting of the
American Society of
Pharmacognosy in 2005 and then
published as a full paper in the peer
reviewed Journal of Agricultural
and Food Chemistry.
A follow-up study on mangosteen
xanthones was recently published
as an abstract, presented as a poster
paper, and a manuscript has been
accepted for publication in the peer
reviewed Journal of Natural
Products. In this work, five additional
xanthones were isolated in
chemically pure form and two of
these had never been isolated from
Nature before. These isolated xanthones
showed powerful cancer
chemopreventive activity in our
quinone reductase induction bioassay
which suggests an inhibition of
cancer initiation.
Focusing on another benefit of
the mangosteen xanthones, several
researchers have published on their
anti-inflammatory properties. For
example, it has been shown that by
neutralizing free radicals, the
polyphenolic xanthones relieve
oxidative stress which, in turn,
reduces inflammation. Other
researchers have demonstrated that
mangosteen xanthones reduce the
production of pro-inflammatory
prostaglandins by inhibiting COX
(cyclooxygenase). My collaboration
with Professor Kinghorn recently
revealed a new
mangosteen xanthone
mechanism.
We found that by
inhibiting a
nuclear factor
called NF-KB, the
xanthones block
the production of
pro-inflammatory
proteins
(cytokines) and enzymes (COX) to
afford a powerful anti-inflammatory
effect. We now have three mechanisms
that can be used to explain
how the xanthones suppress inflammation.
I am sure that many of you
believe that original basic science
research is of paramount
importance. I feel that this belief is
shared by my colleagues because
everyone recognizes the important
correlation between company prestige
and research that supports the
products that we sell. We ask fundamental
questions about product
benefits and then design experiments
that provide the answers.
This approach separates Nature’s
Sunshine from the competition.
After considerable thought, I have
listed below salient points that
define the importance of original
basic science research:
• Verifies and/or establishes
the identity of
actives from an ingredient
• Correlates benefits
with identified actives
• Substantiates the science
behind ingredient
claims
• Establishes ingredient
value
• Confirms Nature’s
Sunshine as an industry
leader through publication
in peer reviewed
scientific journals
• Honours the scientific
integrity of defining and characterizing
the highest quality products
available
• Instills a high degree of consumer
confidence
Again, recognizing, embracing,
and pursuing these points distinguishes
Nature’s Sunshine as a first
class nutritional supplement company.
I have known Professor Doug
Kinghorn for 30 years. He is a
world class scientist in the discipline
of natural product chemistry
(Pharmacognosy). Professor
Kinghorn occupies an endowed
research chair at the prestigious
Ohio State University.
Professor Kinghorn and I
have collaborated on many
projects that focus on
Nature’s Sunshine’s high
quality products. Zambroza
has been a major research
effort for the past four
years. Mangosteen
(Garcinia mangostana), the
core fruit of Zambroza, has
yielded some fascinating
research results.
Xanthones are a class of
plant chemicals that are
found abundantly in mangosteen.
Not only are
the xanthones powerful
Some Of The Science
Behind The Benefits Of
Zambroza™ And Paw Paw Common cold meets
its match in ancient herb
A University of Western Ontario
and University of Alberta team
found that ginseng extracts
"have been found to have the
potential to modulate both natural
and acquired immune
responses." The four-month test
involved 280 subjects between
18 and 65 years of age. At the
conclusion of the test 10% of
the ginseng group reported only
experiencing two or more colds
during the cold/flu season. More
than double that percentage
reported having caught colds in
the placebo group.
In another study from the
Journal of the American
Geriatric Society, 2004, 200 elderly
subjects were given either
ginseng extract or a placebo during
flu season. At the end of the
study, researchers found the
incidence of influenza was considerably
higher in the placebo
group than the ginseng group.
Hand washing best
prevention
According to Health Canada the
best prevention against catching
a virus is frequent hand washing.
Most germs are caught
through hand to eye, face and
mouth contact.
Healthy Bits
Nature’s News
News and information from the world of herbs and nutrition science
by William J. Keller, Ph.D.
Vol. 1/No. 1.
antioxidants, but we also believe
that they possess many other beneficial
effects. Our first scientific
investigation of mangosteen resulted
in the isolation of ten different
xanthones in chemically pure form
and three of these were new from
Nature. Once we determined the
chemical structure of these three
xanthones, we knew that no one
else had ever isolated them. These
pure xanthones were then shown to
have outstanding antioxidant activity.
Further evaluation of these isolated
xanthones suggested cancer
chemoprevention potential. These
data were first published as an
abstract and presented as a poster
paper at the Annual Meeting of the
American Society of
Pharmacognosy in 2005 and then
published as a full paper in the peer
reviewed Journal of Agricultural
and Food Chemistry.
A follow-up study on mangosteen
xanthones was recently published
as an abstract, presented as a poster
paper, and a manuscript has been
accepted for publication in the peer
reviewed Journal of Natural
Products. In this work, five additional
xanthones were isolated in
chemically pure form and two of
these had never been isolated from
Nature before. These isolated xanthones
showed powerful cancer
chemopreventive activity in our
quinone reductase induction bioassay
which suggests an inhibition of
cancer initiation.
Focusing on another benefit of
the mangosteen xanthones, several
researchers have published on their
anti-inflammatory properties. For
example, it has been shown that by
neutralizing free radicals, the
polyphenolic xanthones relieve
oxidative stress which, in turn,
reduces inflammation. Other
researchers have demonstrated that
mangosteen xanthones reduce the
production of pro-inflammatory
prostaglandins by inhibiting COX
(cyclooxygenase). My collaboration
with Professor Kinghorn recently
revealed a new
mangosteen xanthone
mechanism.
We found that by
inhibiting a
nuclear factor
called NF-KB, the
xanthones block
the production of
pro-inflammatory
proteins
(cytokines) and enzymes (COX) to
afford a powerful anti-inflammatory
effect. We now have three mechanisms
that can be used to explain
how the xanthones suppress inflammation.
I am sure that many of you
Study on Ginseng and the Common Cold
Common cold meets
its match in ancient herb
A University of Western Ontario
and University of Alberta team
found that ginseng extracts
"have been found to have the
potential to modulate both natural
and acquired immune
responses." The four-month test
involved 280 subjects between
18 and 65 years of age. At the
conclusion of the test 10% of
the ginseng group reported only
experiencing two or more colds
during the cold/flu season. More
than double that percentage
reported having caught colds in
the placebo group.
In another study from the
Journal of the American
Geriatric Society, 2004, 200 elderly
subjects were given either
ginseng extract or a placebo during
flu season. At the end of the
study, researchers found the
incidence of influenza was considerably
higher in the placebo
group than the ginseng group.
Hand washing best
prevention
According to Health Canada the
best prevention against catching
a virus is frequent hand washing.
Most germs are caught
through hand to eye, face and
mouth contact.
its match in ancient herb
A University of Western Ontario
and University of Alberta team
found that ginseng extracts
"have been found to have the
potential to modulate both natural
and acquired immune
responses." The four-month test
involved 280 subjects between
18 and 65 years of age. At the
conclusion of the test 10% of
the ginseng group reported only
experiencing two or more colds
during the cold/flu season. More
than double that percentage
reported having caught colds in
the placebo group.
In another study from the
Journal of the American
Geriatric Society, 2004, 200 elderly
subjects were given either
ginseng extract or a placebo during
flu season. At the end of the
study, researchers found the
incidence of influenza was considerably
higher in the placebo
group than the ginseng group.
Hand washing best
prevention
According to Health Canada the
best prevention against catching
a virus is frequent hand washing.
Most germs are caught
through hand to eye, face and
mouth contact.
Cancer Facts
Cancer Facts
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
Paw Paw
I am sure that many of you
remember my seminars on Paw
Paw (Asimina triloba) as well as
Paw Paw presentations by Dr. Jerry
McLaughlin, Spence Masson, and
others. Recall that our product Paw
Paw contains a Paw Paw twig
extract. This extract is composed of
over 50 active acetogenins. The fact
that the twigs needed for extraction
are expensive to source (collect)
prompted me to conduct more
research. A collaborative research
project with Dr. Kirk Pomper from
Kentucky State University yielded
some surprising results. We found
that ripe Paw Paw fruits contained
higher concentrations of active acetogenins
as compared to the twigs.
These findings may lead to a less
expensive product because ripe
fruits are much easier to collect and
extract than the twigs.
For a long time it was assumed
that Paw Paw could not be combined
with antioxidants. This old
view suggested to avoid this combination
because the Paw Paw
induced cell apoptosis (programmed
cell death) would be
blocked by antioxidants. The current
view, based on our research
efforts, is that antioxidants have no
effect on Paw Paw’s action. In collaboration
with the Ford Cancer
Center, we have demonstrated that
with cultures of HCT-116 (human
colon cancer) cells, Paw Paw, in
combination with a wide variety of
different antioxidants, including
Zambroza, showed the same effect
as when Paw Paw was used alone.
Furthermore, it appears that antioxidants
may actually complement
Paw Paw. Recently published data
show that antioxidants block cellular
HIF-1 (Hypoxia Induced Factor)
by depriving this protein of needed
free radicals. Without free radicals
HIF-1 does not function and without
HIF-1 cancer cells cannot grow
in anaerobic conditions that occur
when tumours are rapidly growing.
Therefore, it appears that Zambroza
and Paw Paw is a beneficial combination
in most cases.
The science behind pharmacognosy
is fascinating and in this article
I have presented a brief scientific
tale of two products. I believe
that you can now see a correlation
of ingredient actives with the health
benefits of these products. These
correlations are supported by scientific
evidence, much of which came
from our original research. This
original research contributes to the
scientific substantiation of product
value and is a mark of distinction
that characterizes Nature’s
Sunshine. And finally, through this
article you have come away with an
understanding of how an industry
leader creates knowledge that facilitates
the development of their truly
outstanding products.
Cancer Facts
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
remember my seminars on Paw
Paw (Asimina triloba) as well as
Paw Paw presentations by Dr. Jerry
McLaughlin, Spence Masson, and
others. Recall that our product Paw
Paw contains a Paw Paw twig
extract. This extract is composed of
over 50 active acetogenins. The fact
that the twigs needed for extraction
are expensive to source (collect)
prompted me to conduct more
research. A collaborative research
project with Dr. Kirk Pomper from
Kentucky State University yielded
some surprising results. We found
that ripe Paw Paw fruits contained
higher concentrations of active acetogenins
as compared to the twigs.
These findings may lead to a less
expensive product because ripe
fruits are much easier to collect and
extract than the twigs.
For a long time it was assumed
that Paw Paw could not be combined
with antioxidants. This old
view suggested to avoid this combination
because the Paw Paw
induced cell apoptosis (programmed
cell death) would be
blocked by antioxidants. The current
view, based on our research
efforts, is that antioxidants have no
effect on Paw Paw’s action. In collaboration
with the Ford Cancer
Center, we have demonstrated that
with cultures of HCT-116 (human
colon cancer) cells, Paw Paw, in
combination with a wide variety of
different antioxidants, including
Zambroza, showed the same effect
as when Paw Paw was used alone.
Furthermore, it appears that antioxidants
may actually complement
Paw Paw. Recently published data
show that antioxidants block cellular
HIF-1 (Hypoxia Induced Factor)
by depriving this protein of needed
free radicals. Without free radicals
HIF-1 does not function and without
HIF-1 cancer cells cannot grow
in anaerobic conditions that occur
when tumours are rapidly growing.
Therefore, it appears that Zambroza
and Paw Paw is a beneficial combination
in most cases.
The science behind pharmacognosy
is fascinating and in this article
I have presented a brief scientific
tale of two products. I believe
that you can now see a correlation
of ingredient actives with the health
benefits of these products. These
correlations are supported by scientific
evidence, much of which came
from our original research. This
original research contributes to the
scientific substantiation of product
value and is a mark of distinction
that characterizes Nature’s
Sunshine. And finally, through this
article you have come away with an
understanding of how an industry
leader creates knowledge that facilitates
the development of their truly
outstanding products.
Cancer Facts
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
Paw Paw
I am sure that many of you
remember my seminars on Paw
Paw (Asimina triloba) as well as
Paw Paw presentations by Dr. Jerry
McLaughlin, Spence Masson, and
others. Recall that our product Paw
Paw contains a Paw Paw twig
extract. This extract is composed of
over 50 active acetogenins. The fact
that the twigs needed for extraction
are expensive to source (collect)
prompted me to conduct more
research. A collaborative research
project with Dr. Kirk Pomper from
Kentucky State University yielded
some surprising results. We found
that ripe Paw Paw fruits contained
higher concentrations of active acetogenins
as compared to the twigs.
These findings may lead to a less
expensive product because ripe
fruits are much easier to collect and
extract than the twigs.
For a long time it was assumed
that Paw Paw could not be combined
with antioxidants. This old
view suggested to avoid this combination
because the Paw Paw
induced cell apoptosis (programmed
cell death) would be
blocked by antioxidants. The current
view, based on our research
efforts, is that antioxidants have no
effect on Paw Paw’s action. In collaboration
with the Ford Cancer
Center, we have demonstrated that
with cultures of HCT-116 (human
colon cancer) cells, Paw Paw, in
combination with a wide variety of
different antioxidants, including
Zambroza, showed the same effect
as when Paw Paw was used alone.
Furthermore, it appears that antioxidants
may actually complement
Paw Paw. Recently published data
show that antioxidants block cellular
HIF-1 (Hypoxia Induced Factor)
by depriving this protein of needed
free radicals. Without free radicals
HIF-1 does not function and without
HIF-1 cancer cells cannot grow
in anaerobic conditions that occur
when tumours are rapidly growing.
Therefore, it appears that Zambroza
and Paw Paw is a beneficial combination
in most cases.
The science behind pharmacognosy
is fascinating and in this article
I have presented a brief scientific
tale of two products. I believe
that you can now see a correlation
of ingredient actives with the health
benefits of these products. These
correlations are supported by scientific
evidence, much of which came
from our original research. This
original research contributes to the
scientific substantiation of product
value and is a mark of distinction
that characterizes Nature’s
Sunshine. And finally, through this
article you have come away with an
understanding of how an industry
leader creates knowledge that facilitates
the development of their truly
outstanding products.
Cancer Facts
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
remember my seminars on Paw
Paw (Asimina triloba) as well as
Paw Paw presentations by Dr. Jerry
McLaughlin, Spence Masson, and
others. Recall that our product Paw
Paw contains a Paw Paw twig
extract. This extract is composed of
over 50 active acetogenins. The fact
that the twigs needed for extraction
are expensive to source (collect)
prompted me to conduct more
research. A collaborative research
project with Dr. Kirk Pomper from
Kentucky State University yielded
some surprising results. We found
that ripe Paw Paw fruits contained
higher concentrations of active acetogenins
as compared to the twigs.
These findings may lead to a less
expensive product because ripe
fruits are much easier to collect and
extract than the twigs.
For a long time it was assumed
that Paw Paw could not be combined
with antioxidants. This old
view suggested to avoid this combination
because the Paw Paw
induced cell apoptosis (programmed
cell death) would be
blocked by antioxidants. The current
view, based on our research
efforts, is that antioxidants have no
effect on Paw Paw’s action. In collaboration
with the Ford Cancer
Center, we have demonstrated that
with cultures of HCT-116 (human
colon cancer) cells, Paw Paw, in
combination with a wide variety of
different antioxidants, including
Zambroza, showed the same effect
as when Paw Paw was used alone.
Furthermore, it appears that antioxidants
may actually complement
Paw Paw. Recently published data
show that antioxidants block cellular
HIF-1 (Hypoxia Induced Factor)
by depriving this protein of needed
free radicals. Without free radicals
HIF-1 does not function and without
HIF-1 cancer cells cannot grow
in anaerobic conditions that occur
when tumours are rapidly growing.
Therefore, it appears that Zambroza
and Paw Paw is a beneficial combination
in most cases.
The science behind pharmacognosy
is fascinating and in this article
I have presented a brief scientific
tale of two products. I believe
that you can now see a correlation
of ingredient actives with the health
benefits of these products. These
correlations are supported by scientific
evidence, much of which came
from our original research. This
original research contributes to the
scientific substantiation of product
value and is a mark of distinction
that characterizes Nature’s
Sunshine. And finally, through this
article you have come away with an
understanding of how an industry
leader creates knowledge that facilitates
the development of their truly
outstanding products.
Cancer Facts
• 159,900 Canadians will be diagnosed
with cancer in 2007
• 72,700 of those Canadians will
die from the disease
• 1 out of 4 Canadians will die of
cancer
• Men are slightly more likely
than women of developing cancer
• Cancer is the leading cause of
premature death in Canada
Source: Canadian Cancer Society.
Multiple Supplement Users in Better Health
A 2007 study presented in Nutrition
Journal concludes that individuals
who take multiple supplements are
in better health and have fewer diseases
than those who don’t take
supplements or those who take only
a single supplement. According to
the study, this is due to higher
nutrient concentrations in the body.
Disease risk factors that decreased
with the increased use of supplements
included elevated homocysteine
levels, triglycerides, the ratio
of HDL-to-LDL cholesterol, and
the level of pro-inflammatory biomarkers.
In this study those who took multiple
supplements were 73% less
likely to have diabetes. Multiplesupplement
users had a 39%
decrease in the risk of high blood
pressure and had healthier levels of
homocysteine, triglycerides and
LDL cholesterol, risk factors of
heart disease.
Multiple-supplement users were
defined as individuals who took a
multi-vitamin/mineral supplement,
B-complex, vitamins C, E, and D,
antioxidants, omega 3 fatty acids,
and herbal supplements on a regular
basis over a prolonged period of
years.
What’s news in this study is that
it demonstrates the superior health
benefits achieved by taking multiple
combined nutrients in forms of
vitamins, minerals, antioxidants,
fatty acids and herbs. Those who
took just one single supplement—
say vitamin C only—did not fare as
well in the study.
Prestigious medical journal
recommends adults
take supplements to
prevent disease
It wasn’t that long ago that the
Journal of the American Medical
Association startled the medical
world with the recommendation
that, in addition to a healthy
lifestyle, adults take a multi-vitamin/
mineral supplement for the
prevention of chronic life-threatening
diseases. This was an astonishing
admission, since for decades
mainstream medicine would not
budge from its insistence that one
can get all the nutrition needed
from a balanced diet. However,
with mounting evidence and solid
science behind the use of higher
levels of vitamins and minerals,
modern medicine was forced to do
an about-face.
So, follow your doctor’s orders—
with that apple a day, don’t forget
your supplements.
Multiple supplement
users in better health,
Journal concludes that individuals
who take multiple supplements are
in better health and have fewer diseases
than those who don’t take
supplements or those who take only
a single supplement. According to
the study, this is due to higher
nutrient concentrations in the body.
Disease risk factors that decreased
with the increased use of supplements
included elevated homocysteine
levels, triglycerides, the ratio
of HDL-to-LDL cholesterol, and
the level of pro-inflammatory biomarkers.
In this study those who took multiple
supplements were 73% less
likely to have diabetes. Multiplesupplement
users had a 39%
decrease in the risk of high blood
pressure and had healthier levels of
homocysteine, triglycerides and
LDL cholesterol, risk factors of
heart disease.
Multiple-supplement users were
defined as individuals who took a
multi-vitamin/mineral supplement,
B-complex, vitamins C, E, and D,
antioxidants, omega 3 fatty acids,
and herbal supplements on a regular
basis over a prolonged period of
years.
What’s news in this study is that
it demonstrates the superior health
benefits achieved by taking multiple
combined nutrients in forms of
vitamins, minerals, antioxidants,
fatty acids and herbs. Those who
took just one single supplement—
say vitamin C only—did not fare as
well in the study.
Prestigious medical journal
recommends adults
take supplements to
prevent disease
It wasn’t that long ago that the
Journal of the American Medical
Association startled the medical
world with the recommendation
that, in addition to a healthy
lifestyle, adults take a multi-vitamin/
mineral supplement for the
prevention of chronic life-threatening
diseases. This was an astonishing
admission, since for decades
mainstream medicine would not
budge from its insistence that one
can get all the nutrition needed
from a balanced diet. However,
with mounting evidence and solid
science behind the use of higher
levels of vitamins and minerals,
modern medicine was forced to do
an about-face.
So, follow your doctor’s orders—
with that apple a day, don’t forget
your supplements.
Multiple supplement
users in better health,
Garlic
Garlic, that smelly little bulb, more
than any other herb has played a
major role in all cuisines of the
world, and in the medicines of
every great civilization. With such a
reputation it’s not surprising that
this humble vegetable continues to
astound modern researchers.
Although small in size, the clove
of garlic is a source of over 100
health-promoting compounds: 75
different organosulfur compounds
(allicin being one of them),
saponins, polyphenols, selenium,
arginine, vitamin C, potassium and
zinc, to name but a few. As with
most whole foods, garlic's healthpromoting
abilities are probably
due to the sum of the whole, rather
than a single component.
With that said, science has discovered
some compounds are more
abundant than others, and the sulfur-
containing compounds in garlic
appear to be responsible for many
of its powers.
Studies indicate garlic protective
against some cancers
A number of studies have reported
on garlic’s ability to fight cancer,
and research continues to find out
just how. A review of more than
thirty-five studies report some protective
effect against cancer in
about 75% of the published articles.
Garlic supports cardiovascular
health
Garlic has gained lots of attention
for its benefit to cardiovascular
health. Specifically, powerful
antioxidant and anti-inflammatory
compounds in garlic protect LDL
cholesterol from oxidation, raise
levels of HDL cholesterol, improve
triglyceride levels, reduce levels of
heart-damaging homocysteine,
inhibit blood clotting, improve
blood pressure, reduce plaque formation,
and protect against the
damaging affect of free radicals and
toxins such as cigarette smoke.
Powerful antibiotic activity
In the oldest records of medicine
garlic has been used as an antiinfectious
agent.
Four Thieves Vinegar was a concoction
fed to condemned criminals
in the 1700s made of vinegar wine
and crushed garlic. During the
bubonic plague in 1721, as part of
their death sentence, criminals were
condemned to collect dead bodies
and dig their graves. Surprisingly,
the criminals avoided catching the
plague due to the garlic concoction
they drank!
Today, garlic has been the subject
of many studies into its antibiotic
and antiviral powers. Not surprising,
garlic has been shown to
defend against a host of pathogens.
Even antibiotic-resistant strains of
staphylococci have been no match
for garlic.
How to buy garlic supplements
When purchasing garlic supplements
look for a supplement that
provides all the components of
fresh garlic. Some odourless products
have removed important constituents
of the fresh bulb. Look for
a supplement that guarantees
potency.
Cardioprotective effects of garlic found in
various clinical studies
Condition studied % of improvement from garlic
Platelet adhesion 35-58%
(sticking together)
Platelet aggregation 10-25%
(clotting)
LDL cholesterol 5-12%
Total serum cholesterol 6-31+%
Triglycerides 10-19%
Blood pressure 6-8%
Homocysteine 24-35%
LDL oxidation 35-51%
Oxidative damage caused by smoking 29-48%
Microcirculation 67%
than any other herb has played a
major role in all cuisines of the
world, and in the medicines of
every great civilization. With such a
reputation it’s not surprising that
this humble vegetable continues to
astound modern researchers.
Although small in size, the clove
of garlic is a source of over 100
health-promoting compounds: 75
different organosulfur compounds
(allicin being one of them),
saponins, polyphenols, selenium,
arginine, vitamin C, potassium and
zinc, to name but a few. As with
most whole foods, garlic's healthpromoting
abilities are probably
due to the sum of the whole, rather
than a single component.
With that said, science has discovered
some compounds are more
abundant than others, and the sulfur-
containing compounds in garlic
appear to be responsible for many
of its powers.
Studies indicate garlic protective
against some cancers
A number of studies have reported
on garlic’s ability to fight cancer,
and research continues to find out
just how. A review of more than
thirty-five studies report some protective
effect against cancer in
about 75% of the published articles.
Garlic supports cardiovascular
health
Garlic has gained lots of attention
for its benefit to cardiovascular
health. Specifically, powerful
antioxidant and anti-inflammatory
compounds in garlic protect LDL
cholesterol from oxidation, raise
levels of HDL cholesterol, improve
triglyceride levels, reduce levels of
heart-damaging homocysteine,
inhibit blood clotting, improve
blood pressure, reduce plaque formation,
and protect against the
damaging affect of free radicals and
toxins such as cigarette smoke.
Powerful antibiotic activity
In the oldest records of medicine
garlic has been used as an antiinfectious
agent.
Four Thieves Vinegar was a concoction
fed to condemned criminals
in the 1700s made of vinegar wine
and crushed garlic. During the
bubonic plague in 1721, as part of
their death sentence, criminals were
condemned to collect dead bodies
and dig their graves. Surprisingly,
the criminals avoided catching the
plague due to the garlic concoction
they drank!
Today, garlic has been the subject
of many studies into its antibiotic
and antiviral powers. Not surprising,
garlic has been shown to
defend against a host of pathogens.
Even antibiotic-resistant strains of
staphylococci have been no match
for garlic.
How to buy garlic supplements
When purchasing garlic supplements
look for a supplement that
provides all the components of
fresh garlic. Some odourless products
have removed important constituents
of the fresh bulb. Look for
a supplement that guarantees
potency.
Cardioprotective effects of garlic found in
various clinical studies
Condition studied % of improvement from garlic
Platelet adhesion 35-58%
(sticking together)
Platelet aggregation 10-25%
(clotting)
LDL cholesterol 5-12%
Total serum cholesterol 6-31+%
Triglycerides 10-19%
Blood pressure 6-8%
Homocysteine 24-35%
LDL oxidation 35-51%
Oxidative damage caused by smoking 29-48%
Microcirculation 67%
Listen to Your Gut
A healthy intestinal environment is
the very foundation of good health.
And one of the best ways to keep
your intestines in good health is to
ensure a proper balance of gut flora
(friendly bacteria).
Having a healthy population of
gut flora alleviates several uncomfortable
conditions like gas and
bloating, diarrhea, constipation,
Irritable Bowel Syndrome, yeast
overgrowth and general intestinal
discomfort.
But that’s just the beginning. The
benefits of maintaining good intestinal
bacteria levels go far beyond
easing intestinal discomforts. Gut
flora produce certain B vitamins
and even omega-3 fatty acids.
They’re responsible for producing
digestive enzymes like lactase, and
powerful immune factors.
But this critical ecosystem is
fragile and easily disturbed. Some
antibiotics can completely kill off
Hippocrates said...
Eating alone will not keep a
man well; he must also take
exercise. For food and exercise,
while possessing opposite qualities,
yet work together to produce
health.
—Hippocrates, 5th Century
Do vitamins extend
lifespan?
In a UCLA report in 1992 it was
announced that men who took
800 mg a day of vitamin C lived
six years longer than those who
consumed the FDA's recommended
daily allowance of
60 mg a day. The study, which
evaluated 11,348 participants
over a ten year period of time,
showed that high vitamin C
intake extended average life
span and reduced mortality from
cardiovascular disease by 42%.
This study was published in the
journal Epidemiology (1992;
3:3, pp 194-202).
In another study involving
11,178 participants (published in
The American Journal of
Clinical Nutrition August 1996),
those who took vitamin C and E
supplements experienced a 42%
reduction in overall mortality.
Yellow pigment is a
potent antioxidant
Science has discovered that
turmeric, the yellow compound
in curcumin, has some impressive
antioxidant properties.
Some of its published benefits
include cardiovascular support,
and reduced inflammation. You
can find turmeric in the NSP’s
Super Trio Pack.
Healthy Bits
the beneficial bacteria in the gut.
Steroid drugs like cortisone and
prednisone, as well as birth control
pills and chemotherapy can also
upset your gut flora. In addition,
poor nutrition and weak digestion
can impair the efficiency of intestinal
bacteria, as can stress, trauma,
surgery, or parasitic infestation.
When the number or activity
level of your good bacteria drops
too low, it opens the door for harmful
bacteria to proliferate, allowing
the opportunity for diseases to
develop.
Keeping your population of
friendly bacteria up is an important
step to good health. To restore
friendly bacteria take a daily supplement
and you’ll soon be back in
balance.
Supplement daily with
Bifidophilus Flora Force or
Acidophilus/Bifidobacterium.
the very foundation of good health.
And one of the best ways to keep
your intestines in good health is to
ensure a proper balance of gut flora
(friendly bacteria).
Having a healthy population of
gut flora alleviates several uncomfortable
conditions like gas and
bloating, diarrhea, constipation,
Irritable Bowel Syndrome, yeast
overgrowth and general intestinal
discomfort.
But that’s just the beginning. The
benefits of maintaining good intestinal
bacteria levels go far beyond
easing intestinal discomforts. Gut
flora produce certain B vitamins
and even omega-3 fatty acids.
They’re responsible for producing
digestive enzymes like lactase, and
powerful immune factors.
But this critical ecosystem is
fragile and easily disturbed. Some
antibiotics can completely kill off
Hippocrates said...
Eating alone will not keep a
man well; he must also take
exercise. For food and exercise,
while possessing opposite qualities,
yet work together to produce
health.
—Hippocrates, 5th Century
Do vitamins extend
lifespan?
In a UCLA report in 1992 it was
announced that men who took
800 mg a day of vitamin C lived
six years longer than those who
consumed the FDA's recommended
daily allowance of
60 mg a day. The study, which
evaluated 11,348 participants
over a ten year period of time,
showed that high vitamin C
intake extended average life
span and reduced mortality from
cardiovascular disease by 42%.
This study was published in the
journal Epidemiology (1992;
3:3, pp 194-202).
In another study involving
11,178 participants (published in
The American Journal of
Clinical Nutrition August 1996),
those who took vitamin C and E
supplements experienced a 42%
reduction in overall mortality.
Yellow pigment is a
potent antioxidant
Science has discovered that
turmeric, the yellow compound
in curcumin, has some impressive
antioxidant properties.
Some of its published benefits
include cardiovascular support,
and reduced inflammation. You
can find turmeric in the NSP’s
Super Trio Pack.
Healthy Bits
the beneficial bacteria in the gut.
Steroid drugs like cortisone and
prednisone, as well as birth control
pills and chemotherapy can also
upset your gut flora. In addition,
poor nutrition and weak digestion
can impair the efficiency of intestinal
bacteria, as can stress, trauma,
surgery, or parasitic infestation.
When the number or activity
level of your good bacteria drops
too low, it opens the door for harmful
bacteria to proliferate, allowing
the opportunity for diseases to
develop.
Keeping your population of
friendly bacteria up is an important
step to good health. To restore
friendly bacteria take a daily supplement
and you’ll soon be back in
balance.
Supplement daily with
Bifidophilus Flora Force or
Acidophilus/Bifidobacterium.
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